The church of the Holy Trinity of the Spanish, is a church in Rome, in the district Campo Marzio, at the beginning of Via Condotti.
The church and the annexed convent were built by the Spanish Trinitarians between 1741 and 1746, under the pontificate of Benedict XIV, by the Portuguese architect Emanuele Rodriguez dos Santos helped by Giuseppe Sardi.
Around 1880, when the community of the Trinitarian fathers was reduced to a minimum, the Superiors decided to transform the convent into a College for the missions of the Dominicans in the Far East.